Evidence Suggests Microbiome Enterotypes and Prenatal Hormones May Contribute to Chronic Disease Development

Last Updated on: 22nd November 2023, 07:58 am

DervalResearch, a certified B Corp, has presented the findings of a pioneering research study which shows the combined effect of people’s microbiomal and hormonal makeup can predict proneness to chronic disorders and food allergies.

The research, titled ‘Microbiome enterotype, prenatal hormones, and proneness to chronic diseases’, was presented at the Physiology in Focus 2023 conference in Tallinn, Estonia. The study explored the microbiome enterotype, identified via fecal Next Generation DNA-sequencing, and the prenatal hormones evaluated with the digit ratio technique.

Prof. Diana Derval, Chief Investigator of DervalResearch and in charge of the novel research program, said: “Subjects with a Bacteroides microbiome enterotype (E1) and/or more influenced by prenatal testosterone presented a higher prevalence of chronic disorders, including food allergies.”

The chronic diseases reported included atopic dermatitis (AD), asthma, anorexia nervosa (AN), obesity, and osteoporosis, while the reported food allergies were related to cereals and milk.

The research findings have led to the development of an intelligent web-based bot, Microbiot, which is available via the DervalResearch website or by scanning the QR code. This tool helps evaluate one’s microbiome, although a laboratory analysis is still needed to be 100% sure.

The research highlights the potential of targeted health and nutrition plans based on microbiome enterotype and hormonal fingerprint, which could be the key to a better immune system.

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